姓名：李娜娜

职称：副教授

学历：博士研究生

电子邮箱：763043510@qq.com

办公地点：生化楼A410

研究方向：AIE探针的合成及性能研究

所带课程：《分析化学》、《分析化学实验》、《药物分离纯化技术》、《现代光谱分析》、《仪器分析实验》

【个人简介】

李娜娜，2021/06博士毕业于中国海洋大学海洋化学工程与技术专业，一直致力于具有AIE性质荧光探针的开发，在荧光探针的合成及性能研究方面积累了较为丰富的经验，并有良好的研究基础，已经以第一作者在Bioorganic Chemistry、Journal of Molecular Structure、Dyes and Pigments、Journal of Molecular Liquids、Microchemical Journal、Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy、Journal of Molecular Structure、Journal of Photochemistry & Photobiology A: Chemistry、Synthetic Metals 以及Journal of Fluorescence 发表荧光探针的SCI论文15篇。

【教育背景】

2018.09—2021.06 中国海洋大学海洋化学  工程与技术  博士

2015.09—2018.06 东北农业大学  应用化学  硕士

2011.09—2015.06 运城学院  应用化学  学士

【工作经历】

2024.12—至今  忻州师范学院化学系  副教授

2021.09—2024.11  忻州师范学院化学系  讲师

【荣誉获奖】

2021.10  山东省研究生优秀成果奖

2024.09  忻州师范学院科研标兵

【学术兼职】

右江民族医学院  硕士生导师

【主要研究成果】

一、研究课题

1.山西省高等学校科技创新计划项目，构建比色型AIE探针用于可视化显示水稻根系锌镉吸收能力（2022L465），山西省教育厅，2022.09-2024.08，2万，主持。

2.山西省基础研究计划（自由探索类）项目，基于AIE机理构建比色型荧光探针用于镉中毒模型中Zn²⁺和Cd²⁺的联动检测（202203021222307），2023.05-2025.04，5万，主持。

二、代表性论文

[1]Na-Na Li, Wan-Ying Lin, Ying-Ting Wei, Zhan-Bin Jin, Jian-Xia Gu, Hai-long Li, Hai-Xian Ren, Zhi-Yong Xing, Zi-Ao Zong*. Development of an AIE-active fluorescent probe for the simultaneous detection of Al³⁺and viscosity and imaging in Alzheimer’s disease model.Bioorganic Chemistry 2024,152, 107768.

[2]Na-Na Li, Ting-Ting Wei, Zhan-Bin Jin, Cheng-Qi Liu, Zhen Wang, Fengling Li,*, Mohd. Muddassirc, Om Prakash, Abhinav Kumar,*, Jian-Qiang Liu*. A novel dimer induced AIE smart material for fluorescence colorimetric detection of food freshness and Zn²⁺.Journal of Molecular Structure, 2024, 1315, 138985.

[3]Na-Na Li, Yong-E Gao, Xing-Yu Xu, Ping Qiu, Yan Gao, Miao Yan, Qian Zhang,Wan-Ying Lin, Zhi-Yong Xing, Zi-Ao Zong*. Fluorescence probe with aggregation induced emission effect and application for colormetric detection of endogenous and exogenous hypochlorite.Dyes and Pigments, 2023, 210, 110965

[4]Na-Na Li, Xing-Yu Xu, Ping Qiu, Ying-Jin Wan, Hai-Xian Re, Xing-Sheng Yu, Yong-E Gao, Qian Zhan, Mohd. Muddassi, Zhi-Yong Xing. A colormetric and ratiometric AIE probe for imaging endogenous and exogenous hypochlorite.Dyes and Pigments 2023, 219, 111565.

[5]Na-Na Li, Xing-Yu Xu, Ping Qi, Yong-Xia Li, Xiong-Sheng Yu, Yong-E Gao, Hai-Xian Ren, Mohd. Muddassir, Wan-Ying Lin, Zi-Ao Zong. A novel AIE material for sensing of Erythromycin in pure water by hydrogen bond in portable test strips and cellular imaging applications.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2023, 303, 123272.

[6]Na-Na Li* , Wei Wen, Qian Zhang, Yong-E Gao, Zhi-Ying Li, Jie Yang, Hong-Liang Wang, Yu-Ting Du, Yan-Dong Liu. A novel fluorescence sensor for ethyl acetate detection in solution and vapor phase based on addition reaction.Microchemical Journal 2022, 178, 107371

[7]Na-Na Li, Ning-Ning Shi, Wen-Bo Liu, Dong Yang, Zi-Ao Zong, Xia Zhang, Rui-Xue Wu, Cun-Gang Xu, Shuang-Yu Bi**, Yu-Hua Fan*; Solid-State Fluorescent Switch Based On the Intercoversion of J-aggregation and Dimer and Aggregation Pattern-Dependent Fluorescence Colorimetric Sensing of GSH/Zn²⁺/Cd²⁺,Journal of Molecular Liquids, 2021, 342, 116946

[8]Na-Na Li, Zi-wen Lu; Cai-Feng Bi , Jing Xue , Kai-Xuan Ma , Ruixue Wu , Chuan-Bin Fan , Cun-Gang Xu , Xia Zhang* , Yu-Hua Fan*; Rational design and DFT studies of fluorescence probe with dual receptor units for simultaneous multiple targets sensing in aqueous solution along with living cells image and logic gate,Microchemical Journal, 2021, 163, 105898

[9]Na-Na Li, Jing Xue, Xia Zhang, Ning-Ning Shi, Wen-Bo Liu, Rui-Xue Wu, Chuan-Bin Fan, Cun-Gang Xu, Shuang-Yu Bi,**, Yu-Hua Fan*; A novel dimer-induced AIE material as a nano-sensor for colormetric and ratiometric sensing of Erythromycin and metal ions (Zn²⁺, Cd²⁺and Cu²⁺) with different dissociation and re-aggregation processes and cellular imaging applications,Dyes and Pigments, 2021, 184, 108872

[10]Na-Na Li, Wen-Bo Liu, Ning-Ning Shi, Dong Yang, Zi-Ao Zong, Xia Zhang, Rui-Xue Wu, Cun-Gang Xu, Shuang-Yu Bi**, Yu-Hua Fan*; Multiple naphthalimide dimers polymorphs triggered solvatofluorochromism, solid-state emission and aggregation-induced emission by different interaction and its application in fluorescence ratiometric sensing of dichloromethane and 1,4-dioxane,Dyes and Pigments, 2021, 188, 109172

[11]Na-Na Li, Yu-Qing Ma, Xue-Jiao Sun, Ming-Qiang Li, Shuang Zeng, Zhi-Yong Xing*, Jin-Long Li, A dual-function probe based on naphthalene for fluorescent turn-on recognition of Cu²⁺and colorimetric detection of Fe³⁺in neat H₂O,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 210, 266-274

三、专利

李娜娜，高永娥，张倩。一种识别镧离子的荧光探针及其制备方法和应用。专利号：ZL202210739770.2。